Inflammatory bowel disease (IBD): discovering a potential trigger

Inflammatory bowel disease (IBD): Study discovers a possible cause

Within a study he conducted Medical University of Vienna An Austrian research team has now discovered that the cause behind the development of chronic inflammatory bowel disease is… Surface of intestinal epithelial cells You can lie. This discovery offers a potential new starting point in the treatment of chronic inflammatory bowel disease, which until now has primarily aimed to relieve symptoms.

The research team led by Bernadette Modell and Robert Everell observed that changes in the brush borders of intestinal epithelial cells could be linked to the development of inflammatory bowel disease (IBD). Intestinal epithelial cells are specialized cells that make up the inner lining of the intestine. They are closely associated with and form a barrier between the lumen within the intestine and the surrounding tissue. If the intestinal epithelial cells change along with the permeability of the mucous layer, there is an increased risk of developing inflammatory bowel disease. For example, Eating unhealthy foods that contain a high percentage of fat Enhancing the permeability of the mucous layer at the brush border of intestinal epithelial cells.

Also interesting: Frequent bowel movements can be a symptom of these diseases >>

What is inflammatory bowel disease there?

The two most common forms of inflammatory bowel disease are Crohn's disease and ulcerative colitis. Crohn's disease It can affect any part of the digestive system, from the mouth to the anus, causing inflammation that sometimes reaches deep into the intestinal wall. Possible symptoms for those infected include abdominal pain, diarrhea, weight loss, fatigue, and bleeding.

One Ulcerative colitis While it primarily affects the colon and rectum, causing inflammation limited to the inner lining of the intestine. Typical symptoms include bloody diarrhea, abdominal pain and cramps, fever, and weight loss.